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Publikationen

Publikationen aus dem Institut für Immunologie...

Bioinformatics

  1. Fischer G1, Ibrahim SM2, Brockmann GA3, Pahnke J4, Bartocci E5, Thiesen HJ6, Serrano-Fernandez P7, Möller S8 (2003) IF: not yet determined, Times Cited: 2 Expressionview: visualization of quantitative trait loci and gene-expression data in Ensembl. Genome Biol, 4 (11): R 77 1 Proteom-Zentrum Rostock, Germany 3 Züchtungsbiologie und Molekulare Genetik, Institut für Nutztierwissenschaften, Berlin, Germany 4 Universitätsspital, Zürich, Switzerland 2/6 - 8 Institut für Immunologie, Rostock, Germany
  2. Möller S1, Koczan D2, Serrano-Fernandez P3, Zettl UK4, Thiesen HJ5, Ibrahim SM6 (2004) IF: not yet determined, Times Cited: 0 Selecting SNPs for association studies based on population frequencies: a novel interactive tool and its application to polygenic diseases. In Silico Biol, 4 (4): 417-27 1 - 3/5 - 6 Institut für Immunologie, Rostock, Germany 4 Klinik und Poliklinik für Neurologie, Rostock, Germany
  3. Serrano-Fernandez P1, Ibrahim SM2, Zettl UK3,Thiesen HJ4, Gödde R5, Eppeln JT6, Möller S7 (2004) IF: 3.6370, Times Cited: 1 Intergenomic consensus in multifactorial inheritance loci: the case of multiple sclerosis. Genes Immun, 5 (8): 615-20 1 - 2/4/7 Institut für Immunologie, Rostock, Germany 3 Klinik und Poliklinik für Neurologie, Rostock, Germany 5 - 6 Ruhr-Universität, Abteilung für Molekulare Humangenetik, Bochum, Germany
  4. Möller S1, Mix E2, Blüggel, M3, Serrnao-Fernandez P4, Koczan D5, Kotsikoris V6, Kunz M7, Watson M8, Pahnke J9, Illges H10, Kreutzer M11, Mikkat S12, Thiesen HJ13, Glocker MO14, Zettl, UK15, Ibrahim SM16 (2005) IF: not yet determined, Times Cited: Collection of soluble variants of membrane proteins for transcriptomics and proteomics. In Silico Biology 5, 0028, Bioinformation Systems e.V. 1/4- 6/13/16 Institute of Immunology, Rostock, Germany 2/15 Department of Neurology, Rostock, Germany 3 Protagen AG, Dortmund, Germany 7 Department of Dermatology, Rostock,Germany 8 Institute for Animal Health, Newbury,UK 9 Department of Pathology, Zürich, Switzerland 10 Biotechnologie Institut, Tägerwilen, Switzerland 11 - 12/14 Proetome Center, Rostock, Germany

Functional Genomics

  1. Bray P1, Thiesen HJ2 (1990) IF: Journal did not survive, Times Cited: 1 Putting the finger on DNA. Zinc Finger Gene Meeting sponsored by the Imperical Cancer Research Fund, London, UK, February 15-16, 1990. New Biol, 2 (4): 325-7 1 Laboratory of Molecular Genetics, National Institutes of Health, Bethesda, 2 Basel Institute for Immunology, Switzerland
  2. Thiesen HJ1 (1990) IF: Journal did not survive, Times Cited: 72 Multiple genes encoding zinc finger domains are expressed in human T cells. New Biol, 2 (4): 363-74 1 Basel Insitute for Immunology, Switzerland
  3. Thiesen HJ1, Bellefroid E2, Revelant O3, Martial JA4 (1991) IF: 6.575, Times cited: 13 Conserved KRAB protein domain identified upstream from the zinc finger region of Kox 8. Nucleic Acids Res, 19 (14): 3996 1 Basel Institute for Immunology, Switzerland 2 - 4 Laboratoire de Biologie Moleculaire et de Genie Genetique, Universite de Liege, Belgium
  4. Thiesen HJ1, Meyer W2 (1993) IF: 1.892,Times cited: 7 Krab domains analysed in humanCys/His-type zinc-finger proteins KOX 1, KOX 8, and KOX 19. Ann N Y Acad Si, 684:243-5 1 - 2 Basel Institute for Immunology, Switzerland
  5. Rousseau-Merck MF1, Hillion J2, Jonveaux P3, Couillin P4, Seite P5, Thiesen HJ6, Berger R7 (1993) IF: 4.022, Times Cited: 21 Chromosomal localization of 9 KOX zinc finger genes: physical linkages suggest clustering of KOX genes on chromosomes 12, 16 and 19. Hum Genet, 92 (6): 583-7 1 - 3/5/7 INSERM U. 310, Institut de Genetique Moleculaire, Paris, France 4 INSERM U.178, Paul-Vaillant-Couturier, Villejuif Cedex, France 6 Basel Institute for Immunology, Switzerland
  6. Margolin JF1, Friedman JR2, Meyer WK3, Vissing H4, Thiesen HJ5, Rauscher FJ 3rd6 (1994) IF: 10.272, Times Cited: 257 Kruppel-associated boxes are potent transcriptional repression domains. Proc Natl Acad Sci USA, 91 (10): 4509-13 1 - 2/6 Wistar Institute, Philadelphia, USA 3/5 Basel Institute for Immunology, Switzerland 4 Novodisk, Denmark
  7. Deuschle U1, Meyer WK2,Thiesen HJ3 (1995) IF: 8.142, Times cited: 99 Tetracycline-reversible silencing of eukaryotic potomters. Mol Cell Biol, 15 (4): 1907-14 1 - 3 Basel Institute for Immunology, Switzerland
  8. Lange R1, Christoph A2,Thiesen HJ3, Vopper G4, Johnson KR5, Lemaire L6, Plomann M7, Cremer H8, Barthels D9, Heinlein UA10 (1995) IF: 2.006, Times cited: 25 Developmentally regulated mouse gene NK 10 encodes a zinc finger repressor protein with differential DNA-binding domains. DNA Cell Biol, 14 (11): 971-81 1 - 2/7 - 9 Institut für Genetik, Universität zu Köln, Germany 3 Basel Institute for Immunology, Switzerland 4/10 Institut für Genetik, Universität zu Köln, Germany 5 The Jackson Laboratory, Bar Harbor, ME 04609 6 Institut für Genetik, Heinrich-Heine-Universität, Düsseldorf, Germany
  9. Vissing H1, Meyer WK2, Aagaard L3, Tommerup N4, Thiesen HJ5 (1995) IF: 3.609, Times Cited: 68 Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins. FEBS Lett, 369 (2-3): 153-7 1 - 4 Novodisk, Denmark 5 Basel Institute for Immunology, Switzerland
  10. Moosmann P1, Georgiev O2, Thiesen HJ3, Hagmann M4, Schaffner W5 (1997) IF: 3.366, Times cited: 31 Silencing of RNA polymerases II and III-dependent transcription by the KRAB protein domain of KOX 1, a Kruppel-type zinc finger factor. Biol Chem, 378 (7): 669-77 1 - 2/4 - 5 Institut für Molekularbiologie der Universität Zürich, Zürich, Switzerland 3 Institut für Immunologie, Rostock, Germany
  11. Schröder P1, Meyer L2, Wheeler TT3, Thiesen HJ4, Seyfert HM5 (1998) IF: not found, Times Cited: 6 Cloning and sequencing of the bovine STAT5A cDNA reveals significant sequence divergence with ovine. Biochim Biophys Acta, 1398 (2): 99-105 1 - 2/5 Forschungsinstitut für die Biologie landwirtschaftlicher Nutztiere, Dummerstorf, Germany 3 AgResearch Ruakura, Private Bag 3123; Hamilton, New Zealand 4 Institut für Immunologie, Rostock, Germany
  12. Seyfert HM1, Pitra C2, Meyer L3, Brunner RM4, Wheeler TT5, Molenaar A6, McCracken JY7, Herrmann J8,Thiesen HJ9, Schwerin M10 (2000) IF: 3.114,Times Cited: 10 Molecular characterization of STAT5A- and STAT5B-encoding genes reveals extended intragenic sequence homogeneity in cattle and mouse and different degrees of divergent evolution of various domains. J Mol Evol, 50 (6): 550-61 1/3 - 4/8/10 Research Institute for the Biology of Fram Animals, Dummerstorf, Germany 2 Institue of Zoo Biology and Wildlife Research, Berlin, Germany 5 - 7 AgResearch, Ruakura Research Centre, Hamilton, New Zealand 9 Institut für Immunologie, Rostock, Germany
  13. Lorenz P1, Koczan D2, Thiesen HJ3 (2001) IF: 3.366, Times Cited:5 Transcriptional repression mediated by the KRAB domain of the human C2H2 zinc finger protein Kox 1/ZNF 10 does not require histone deacetylation. Biol Chem, 382 (4): 637-44 1 - 3 Institut für Immunologie, Rostock, Germany
  14. Rousseau-Merck MF1, Koczan D2, Legrand I3, Möller S4, Autran S5, Thiesen HJ6 (2002) IF: 0.497,Times Cited: 2 The KOX zinc finger genes: genome wide mapping of 368 ZNF PAC clones with chromosomal loci are confirmed by human sequences annotated in EnsEMBL. Cytogenet Genome Res, 98 (2 - 3): 147-53 1/3 INSERM U 509, Institut Curie, Paris,France 2/4/6 Institut für Immunologie, Rostock, Germany

Genomics

  1. Rousseau-Merck MF1, Huebner K2, Berger R3, Thiesen HJ4 (1991) IF: 3.488, Times cited: 18 Chromosomal localization of two human zinc finger protein genes, ZNF 24 (KOX 17) and ZNF 29 (KOX 26), o 18q12 and 17p13-p12, respectively. Genomics, 9 (1): 154-61 1 INSERM U. 301, CNRS, Hospital Saint-Louis, Paris,France 2 Fels Institute for Cancer Research and Molecular Biology, Philadelphia, Pennsylvania 3 INSERM U. 301, CNRS, Hospital Saint-Louis, Paris,France 4 Basel Institute for Immunology, Switzerland
  2. Huebner K1, Druck T2, Croce CM3, Thiesen HJ4 (1991) IF: 11.602, Times Cited: 103 Twenty-seven novoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering. Am J Hum Genet, 48 (4): 726-40 1 - 3 Fels Institute for Cancer Research and Molecular Biology, Philadelphia 4 Basel Institute for Immunology, Switzerland
  3. Seite P1, Huebner K2, Rousseau-Merck MF3, Berger R4, Thiesen HJ5 (1991) IF: 4.022, Times Cited: 16 Two human genes encoding zinc finger proteins, ZNF 12 (KOX 3) and ZNF 26 (KOX 20), map to chromosome 7p22-p21 and 12q24.33, respectively. Hum Genet, 86 (6): 585-90 1/3/4 INSERM U, 301 Institut de Genetique Moleculaire, Paris, France 2 Fels Institute for Cancer Research and Molecular Biology, Philadelphia, USA 5 Basel Institute for Immunology, Switzerland
  4. Bray P1, Lichter P2, Thiesen HJ3, Ward DC4, Dawid IB5 (1991) IF: 10,272, Times cited: 48 Characterization and mapping of human genes encoding zinc finger proteins. Proc Natl Acad Sci USA, 88 (21): 9563-7 1/5 Laboratory of Molecular Genetics, Bethesda 2 Department of Genetics, New Haven; DKFZ Heidelberg 3 Basel Institute for Immunology, Switzerland 4 Department of Genetics, New Haven
  5. Rousseau-Merck MF1, Tunnacliffe A2, Berger A3, Ponder BA4, Thiesen HJ5 (1992) IF: 3.488, Times Cited: 33 A cluster of expressed zinc finger protein genes in the pericentromeric region of human chromosome 10. Genomics, 13 (3): 845-8 1/3 INSERM U. 301 and SDI 15954 I CNRS, Hopiatl Saint-Louis, Paris, France 2/4 CRC Human Cancer Genetics Research Group, Cambridge, UK 5 Basel Institute for Immunology, Switzerland
  6. La Pillo B1, Ludecke HJ2, Thiesen HJ3, Horsthemke B4 (1993) IF: 8.597, Times cited: 1 A BanII RFLP in the ZNF 34 zinc finger gene on chromosome 8. Hum Mol Genet, 2 (8), 1331 1 - 4 Institut für Humangenetik, Universitätsklinikum Essen, Germany
  7. Tunnacliffe A1, Liu L2, Moore JK3, Leversha MA4, Jackson MS5, Papi L6, Ferguson-Smith MA7, Thiesen HJ8, Ponder BA9 (1993) IF: 6.575, Times Cited:35 Duplicated KOX zinc finger clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution. Nucleic Acids Res, 21 (6): 1409-17 1/3/5/9 CRC Human Cancer Genetics Research Group, Cambridge, UK 2 Department of Neurobiology Cambridge, UK 4/7 Human Molecular Genetics, University of Cambridge, Cambridge, UK 6 Department of Clinical Physiopathology, Firenze, Italy 8 Basel Institute for Immunology, Switzerland
  8. Cannizzaro LA1, Aronson MM2, Thiesen HJ3 (1993) IF: 4.022, Times Cited: 14 Human zinc finger gene ZNF 23 (Kox 16) maps to a zinc finger gene cluster on chromosome 16q22, and ZNF 32 (Kox 30) to chromosome region 10q23-q24. Hum Genet, 91 (4): 383-5 1 - 2 Fels Institute for Cancer Research and Molecular Biology, Philadelphia, USA 3 Basel Institute for Immunology, Switzerland
  9. Knight JC1, Grimaldi G2, Thiesen HJ3, Bech-Hansen NT4, Fletcher CD5, Coleman MP6 (1994) IF: 3.488, Times Cited: 24 Clustered organization of Kruppel zinc-finger genes at Xp11.23, flanking a translocation breakpoint at OATL1: a physical map with locus assignments for ZNF 21, ZKF 41, ZNF 81, and ELK1. Genomics, 21 (1): 180-7 1/5 Department of Histopathology, UMDS, London, UK 2 International Institute of Genetics and Biophysics, naples, Italy 3 Basel Institute for Immunology, Switzerland 4 Department of Paediatrics, Alberta Childrens Hospital, Calgary,Canada 6 Institute of Molecular Medicine, Headington, UK
  10. Rousseau-Merck MF1, Duro D2, Berger R3, Thiesen HJ4 (1995) IF:0.617, Times Cited: 3 Chromosomal localization of two KOX zinc finger genes on chromosome bands 7q21-q22. Ann Genet, 38 (2): 81-4 1 - 3 INSERM U. 310, Institut de Genetique Moleculaire, Paris, France 4 Basel Institute for Immunology, Switzerland
  11. Guy J1, Hearn T2, Crosier M3, Mudge J4, Viggiano L5, Koczan D6, Thiesen HJ7, Bailey JA8, Horvath JE9, Eichler EE10, Earthrowl ME11, Deloukas P12, French L13, Rogers J14, Bentley D15, Jackson MS16 (2003) IF: 9.635, Times Cited: 20 Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p. Genome Res, 13 (2): 159-72 1 - 4/16 The Institute of Human Genetics, University of Newcastle upon Tyne, UK 5 DAPEG, Sezione di Genetica,Bari Italy 6 - 7 Institut für Immunologie, Rostock, Germany 8 - 10 Department of Genetics and Center for Human Genetics, Cleveland, Ohio, USA 11 - 15 The Wellcome Trust Sanger Institute, Cambridge, UK

Immunology

  1. Arndt R1, Thiesen HJ2 (1985) IF: 1.942, Times Cited: 1 Elimination of trinitrophenol-specific antibody response by antigen-toxin conjugates. Scand J Immunol, 22 (5): 489-94 1-2 UKE Hamburg, Germany
  2. Ibrahim SM1, Mix E2, Böttcher T3, Koczan D4, Gold R5, Rolfs A6, Thiesen HJ7 (2001) IF: 7.967,Times Cited: 36 Gene expression profiling of the nervous system in murine experimental autoimmune encephalomyelitis. Brain, 124 (Pt 10): 1927-38 1/4/7 Institut für Immunologie, Rostock, Germany 2,3/6 Klinik und Poliklinik für Neurologie, Rostock, Germany 5 Klinische Forschergruppe für Multiple Sklerosis, Würzburg, Germany
  3. Wandschneider S1, Fehring V2, Jacobs-Emeis S3, Thiesen HJ4, Löhr M5 (2001) IF: 4.040. Times Cited: 5 Autoimmune pancreatic disease. preparation of pancreatic juice for proteome analysis. Electrophoresis, 22 (20): 4383-90 1-2 Proteom-Zentrum Rostock, Germany 4 Institut für Immunologie, Rostock, Germany 5 Abteilung für Medizin IV, Medizinische Fakultät Mannheim, Universität Heidelberg, Germany
  4. Ibrahim SM1, Koczan D2, Thiesen HJ3 (2002) IF: 2.353, Times cited: 13 Gene-expression profile of collagen-induced arthritis. J Autoimmun, 18 (2): 159-67 1-3 Institut für Immunologie, Rostock, Germany
  5. Ma Y1, Liu H2, Tu-Rapp H3, Thiesen HJ4, Ibrahim SM5, Cole SM6, Pope RM7 (2004) IF: 28.1800, Times Cited: 7 Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation. Nat Immunol, 5 (4): 380-7 1 Northwestern University Feinberg School of Medicine and Veteran's Administration Medical Center, Chicago, USA 3-5 Institute of Immunology, Rostock, Germany
  6. Mix E1, Ibrahim SM2, Pahnke J3, Koczan D4, Sina C5, Böttcher T6, Thiesen HJ7, Rolfs A8 (2004) IF: 3.0540, Times Cited: 0 Gene-expression profiling of the early stages of MOG-induced EAE proves EAE-resistance as an active process. J Neuroimmunol, 151 (1-2):158-70 1/6/8 Klinik und Poliklinik für Neurologie, Rostock, Germany 2/4-5/7 Institut für Immunologie, Rostock, Germany 3 Universitätsspital, Zürich, Switzerland
  7. Bauer K1, Yu X2, Wernhoff P3, Koczan D4, Thiesen HJ5, Ibrahim SM6 (2004) IF: 7.1900, Times Cited: 0 Identification of new quantitative trait loci in mice with collagen-induced arthritis. Arthritis Rheum, 50 (11): 3721-8 1-6 Institut für Immunologie, Rostock, Germany
  8. Claus R1, Lenschow U2, Külz T3, Kotitschke A4, Meiske D5, Thiesen HJ6, Lorenz P7 (2005) IF: 3.760, Times Cited: 0 Congenital heart block associated with a maternal anti-HsEg5-like autoantibody. Rheumatology (Oxford), 44 (5): 691-3 1/4-7 Institut für Immunologie, Rostock, Germany 2 Universitätskinder- und Jugendklinik, Rostock, Germany 3 Frauenklinik und Poliklinik, Rostock, Germany
  9. Koczan D1, Guthke R2, Thiesen HJ3, Ibrahim SM4, Kundt G5, Krentz H6, Gross G7, Kunz M8 (2005), IF: 0.987 Gene expression profiling of peripheral blood mononuclear leukocytes from psoriasis patients identifies new immune regulatory molecules. European Journal of Dermatology (in press) 1/3-4 Institute of Immunology, Rostock, Germany 2 Knoell-Institute for Natural Products Reserch, Jena, Germany 5-6 Institute for Medical Informatics and Biometry, Rostock, Germany 7-8 Department of Dermatology and Venerology, Rostock, Germany
  10. Palaez IM1, Vogler S2, Strauß U3, Wernhoff P4, Pahnke J5, Brockmann G6, Moch H7, Thiesen HJ8, Rolfs A9, Ibrahim SM10 (2005), IF: 8.597 Identification of quantitative trait loci controlling cortical motor evoked potentials in experimental autoimmune encephalomyelitis: Correlation with incidence, onset and severity of disease. Human Molecular Genetics (in press) 1-2/4/8/10 Department of Immunology, Rostock, Germany 3/5/9 Department of Neurology, Rostock, Germany 6 Institut of Animal science, Berlin, Germany 7 Department of Pathology, Zürich,Switzerland

Inorgenic Biochemistry

  1. Thiesen HJ1, Bach C2 (1991) IF: 2.836, Times Cited: 52 Transition metals modulate DNA-protein interactions of SP 1 zinc finger domains with its cognate target site. Biochem Biophys Res Commun, 176(2): 551-7 1-2 Basel Institute for Immunology, Switzerland

Neurology

  1. Pott U1, Thiesen HJ2, Colello RJ3, Schwab ME4 (1995) IF:4.825, Times Cited: 14 A new Cys2/His2 zinc finger gene rKr2, is expressed in differentiated rat oligodendrocytes and encodes a protein with a functional repressor domain. J Neurochem, 65(5): 1955-66 1/3-4 Brain Research Institute, University of Zürich, Switzerland 2 Basel Institute for Immunology, Switzerland
  2. Böttcher T1, Mix E2, Koczan, D3, Bauer P4, Pahnke J5, Peters S6, Weinelt S7, Knoblich R8, Strauss U9, Cattaneo E10, Thiesen HJ11, Rolfs A12 (2003) IF: 3.374,Times cited: 3 Gene expression profiling of ciliary neurotrophic factor-overexpressing rat striatal progenitor cells (ST14A) indicates improved stress response during the early stage of differentiation. J Neurosci Res, 73 (1): 42-53 1,2/4-9 Neurobiological Laboratori, Department of Neurology, Rostock, Germany 3/11 Institute of Immunology, Rostock, Germany 4 Institute of Medical Genetics, Tübingen, Germany 10 Institute of Pharmacological Sciences, Milan, Italy
  3. Pahnke J1, Mix E2, Knoblich R3 Müller J4, Zschiesche M5,Schubert B6, Koczan D7, Bauer P8, Böttcher T9,Thiesen HJ10, Lazarov L11, Wree A12, Rolfs A13 (2004) IF: 3.9490, Times Cited: Overexpression of glial cell line-derived neurotrophic factor induces genes regulating migration and differentiation of neuronal progenitor cells. Exp Cell Res, 297 (2): 484-94 1 Universitätsspital, Zürich, Switzerland; Institut für Neurologie, Rostock, Germany 2-6/9/13 Klinik und Poliklinik für Neurologie, Rostock, Germany 7/10 Institut für Immunologie, Rostock, Germany 8 Institut für Medizinische Genetik, Tübingen, Germany 11 Institut für Pathologie, Rostock, Germany 12 Institut für Anatomie, Rostock, Germany

Oncology

  1. Thiesen HJ1, Juhl H2, Arndt R3 (1987) IF: 8.649, Times Cited: 11 Selective killing of human bladder cancer cells by combined treatment with A and B chain ricin antibody conjugates. Cancer Res, 47 (2): 419-23 1 EMBL Heidelberg 2-3 UKE Hamburg
  2. Lim FL1, Soulez M2, Koczan D3, Thiesen HJ4, Knight JC5 (1998) IF:6.495,Times cited: 40 A KRAB-related domain an a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas. Oncogene, 17 (15): 2013-8 1,2 Department of Cancer Medicine, Imperial College of Science, London, UK 3,4 Institut für Immunologie, Rostock, Germany 5 Department of Histopathology, UMDS, London, UK
  3. Ringel B1, Ibrahim SM2, Köhler H3, Ringel J4, Koczan D5, Liebe S6, Löhr M7, Thiesen HJ8 (1999) IF: 1.892, Times cited: 0 Apoptotic molecules in pancreatic carcinoma cell lines. Ann N Y Acad Sci, 880:175-8 1-3/5/8 Institut für Immunologie, Rostock, Germany 4/6/7 Klinik und Poliklinik für Innere Medizin, Abt. Gastroenterologie, Rostock, Germany
  4. Kunz M1, Hartmann A2, Flory E3, Toksoy A4, Koczan D5, Thiesen HJ6, Mukaida N7, Neumann M8, Rapp UR9, Brocker EB10, Gillitzer R11 (1999) IF: 6.946, Times Cited: 47 Anoxia-induced up-regulation of interleukin-8 human malignant melanoma. A potential mechanism for high tumor aggressiveness. Am J Pathol, 155 (3): 753-63 1 Klinik und Poliklinik für Dermatologie und Venerologie, Rostock, Germany 2/4/10-11 Klinik für Dermatologie, Würzburg, Germany 3 Institut für Medizinsche Strahlenkunde und Zellforschung 5/6 Institut für Immunologie, Rostock, Germany 7 Kanazawa-Universität, Japan 8 Institut für Pathologie
  5. Reimer T1, Koczan D2, Müller H3, Friese K4, Krause A5, Thiesen HJ6, Gerber B7 (2000) IF: 3.701, Times Cited: 9 Human chorionic gonadotrophin-beta transcripts correlate with progesterone receptor values in breast carcinomas J Mol Endocrinol, 24 (1): 33-41 1/4/5/7 Frauenklinik und Poliklinik, Rostock, Germany 2/6 Institut für Immunologie, Rostock, Germany
  6. Reimer T1, Herrnring C2, Koczan D3, Richter D4, Gerber B5, Kabelitz D6, Friese K7, Thiesen HJ8 (2000) IF: 8.649,Times Cited: 45 Fas L: Fas ratio - a prognostic factor in breast carcinomas. Cancer Res, 60 (4): 822-8 1/2/4/5/7 Frauenklinik und Poliklinik, Rostock, Germany 6 Paul-Ehrlich-Institut, Langen, Germany 3/8 Institut für Immunologie, Rostock, Germany
  7. Kunz M1, Ibrahim S2, Koczan D3, Thiesen HJ4, Köhler H5, Acker T6, Plate KH7, Ludwig S8, Rapp UR9, Brocker EB10, van Muijen GN11, Flory E12, Gross G13 (2001) IF: 4.384,Times Cited: 13 Activation of c-Jun NH2-terminal kinase/stress-activated protein kinase (JNK/SAPK) is critical for hypoxia-induced apoptosis of human malignant melanoma. 1/4/7 Cell Growth Differ, 12 (3): 137-45 1/13 Klinik und Poliklinik für Dermatologie und Venerologie, Rostock, Germany 2-5 Institut für Immunologie, Rostock, Germany 6-7 Institut für Neuropathologie, Erlangen, Germany 8-9 Institut für Strahlenkunde und Zellforschung, Würzburg, Germany 10 Institut für Dermatologie, Würzburg, Germany 11 Institut für Pathologie, Nijmagen, NL 12 Paul-Ehrlich-Institut, Langen, Germany
  8. Ibrahim SM1, Ringel J2, Schmidt C3, Ringel B4, Müller P5, Koczan D6, Thiesen HJ7, Löhr M8 (2001) IF: 1.855, Times cited: 18 Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death. Pancreas, 23 (1): 72-9 1-7 Institut für Immunologie, Rostock, Germany 8 Abteilung für Medizin IV, Medizinische Fakultät Mannheim, Universität Heidelberg, Germany
  9. Reimer T1, Koczan D2, Müller H3, Friese K4, Thiesen HJ5, Gerber B6 (2002) IF: 2.932, Times Cited: 6 Tumour Fas ligand: Fas ratio greater than 1 is an independent marker of relative resistance to tamoxifen therapy in hormone receptor positive breast cancer. Breast Cancer Res, 4 (5): R 9 1/3,4/6 Frauenklinik und Poliklinik, Rostock, Germany 2/5 Institut für Immunologie, Rostock, Germany
  10. Kunz M1, Koczan D2, Ibrahim SM3,Gillitzer R4, Gross G5, Thiesen HJ6 (2002) IF: 0.670 Times Cited: 5 Differential expression of thrombospondin 2 in primary and metastatic malignant melanoma. Acta Derm Venereol, 82 (3): 163-9 1/5 Klinik und Poliklinik für Dermatologie und Venerologie, Rostock, Germany 2,3/6 Institut für Immunologie, Rostock, Germany 4 Klinik für Dermatologie, Würzburg, Germany
  11. Benz S1, Löbler M2, Obermaier R3, Kortmann B4, Pfeffer F5, Koczan D6, Thiesen HJ7, Hopt UT8 (2002) IF: 0.588, Times Cited: 2 New possible target genes in pancreatic ischemia/reperfusion-injury identified by microarray analysis. Transplant Proc, 34 (6): 2369-71 1/3,4 Department of General Surgery, Freiburg, Gemany 2 Fachbereich Biowissenschaften der Univeristät Rostock, Rostock, Germany 5 Klinik und Poliklinik für Chirurgie, Rostock, Gemany 6/7 Institut für Immunologie, Rostock, Germany 8 Chirurgische Klinik und Poliklinik, Rostock, Germany
  12. Kunz M1, Möller S2, Koczan D3, Lorenz P4, Wenger RH5,Glocker MO6, Thiesen HJ7, Gross G8, Ibrahim SM9 (2003) IF: 6.482, Times Cited: 7 Mechanisms of hypoxic gene regulation of angiogenesis factor Cyr 61 in melanoma cells. J Biol Chem, 278 (46): 45651-60 1/5/8 Klinik und Poliklinik für Dermatologie und Venerologie, Rostock, Germany 2-4/7/9 Institut für Immunologie, Rostock, Germany 6 Proteom-Zentrum Rostock, Germany
  13. Brocke-Heidrich K1, Kretzschmar AK2, Pfeifer G3, Henze C4, Löffler D5, Koczan D6, Thiesen HJ7, Burger R8, Gramatzki M9, Horn F10 (2004) IF: 10.1200, Times Cited: 4 Interleukin-6-dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family-independent survival pathway closely associated with Stat 3 activation. Blood, 103 (1): 242-5 1 Institut für Klinische Immunologie und Transfusionsmedizin, Leipzig, Germany Institut für Immunologie, Rostock, Germany Division of Hematology/Onclogy, Erlangen, Germany
  14. Sparmann G1, Hohenadl C2, Tornoe J3, Jaster R4, Fitzner B5, Koczan D6, Thiesen HJ7, Glass Ä8, Winder D9, Liebe S10, Emmrich J11 (2004) IF: 3.4210, Times Cited: 0 Generation and characterization of immortalized rat pancreatic stellate cells. Am J Physiol Gastrointest Liver Physiol, 287 (1): G 211-9 1/4-5/10,11 Department of Gastroenterology, Rostock, Germany 2/9 Insitute of Virology, Vienna, Austria 3 NsGene A/S, Ballerup, Denmark 6-7 Institute of Immunology, Rostock, Germany 8 Institute of Medical Informatics and Biometry, Rostock, Germany
  15. Strauss LG1, Dimitrakopoulou-Strauss A2, Koczan D3, Bernd L4, Haberkorn U5, Ewerbeck V6, Thiesen HJ7 (2004) IF: 4.8990, Times Cited: 0 18F-FDG kinetics and gene expression in giant cell tumors. J Nucl Med, 45 (9): 1528-35 1-2 Clinical Cooperation Unit Nuclear Medicine, Heidelberg,Germany 3/7 Institut für Immunologie, Rostock, Germany
  16. Pfeffer F1, Koczan D2, Adam U3, Benz S4, von Dobschütz E5, Prall F6, Nizze H7, Thiesen HJ8, Hopt UT9, Lölbler M10 (2004) IF: 1.8550,Times Cited: 0 Expression of connexin 26 in islets of Langerhans is associated with impaired glucose tolerance in patients with pancreatic adenocarcinoma. Pancreas, 29 (4): 284-90 1/3-6/9,10 Klinik und Poliklinik für Chirurgie,Rostock Germany 2/8 Institut für Immunologie, Rostock, Germany 7 Institut für Pathologie, Rostock, Germany
  17. Bader JE1, Deckert CM2, Koglin N3, Pluder F4, Mörl K5, Koczan D6, Thiesen HJ7, Beck-Sickinger AG8 (2004) IF: 1.0930, Times Cited: 0 From transcription profile to expression: the signalling repertoire of the SK-N-MC neuroepithelioma cell-line. Recept Signal Transduct Res, 24(4): 257-82 1-5/8 Faculty of Biosciences, Pharmacy and Psychology, Institut of Biochemistry, Leipzig, Germany 6-7 Institut für Immunologie, Rostock, Germany

Obstetrics

  1. Reimer T1, Koczan D2, Gerber B3, Richter D4, Thiesen HJ5, Friese K6 (2002) IF: 3.067, Times Cited: 7 Microarray analysis of differentially expressed genes in placental tissue of pre-eclampsia: up-regulation of obesity-related genes. Mol Hum Reprod, 8 (7): 674-80 1/3,4/6 Frauenklinik und Poliklinik, Rostock, Germany 2/5 Institut für Immunologie, Rostock, Germany

Proteomics

  1. Berlau J1, Lorenz P2, Beck R3, Makovitzky J4, Schlotzer-Schrehardt U5, Thiesen HJ6, Guthoff R7 (2001) IF: 1.272, Times Cited: 4 Analysis of aqueous humour proteins of eyes with and without pseudoexfoliation syndrome. Graefes Arch Clin Exp Ophthalmol, 239 (10), 743-6 1/3/7 Augenklinik und Poliklinik, Rostock, Germany 2/6 Institut für Immunologie, Rostock, Germany
  2. Sinz, A1, Bantscheff M2, Mikkat S3, Ringel B4, Drynda S5, Kekow J6, Thiesen HJ7, Glocker MO8 (2002) IF: 4.040, Times Cited: 26 Mass spectrometric proteome analysis of synovial fluids and plasmas from patients suffering from rheumatoid arthritis and comparison to reactice arthritis or osteoarthritis. Electrophoresis, 23 (19): 3445-56 1-4/8 Proteom-Zentrum Rostock, Germany 5-6 Klinik für Rheumatologie Vogelsang, Germany 7 Institut für Immunologie, Rostock, Germany
  3. Madi A1, Mikkat S2, Ringel B3, Thiesen HJ4, Glocker MO5 (2003) IF: 4.040,Times Cited: 3 Profiling stage-dependent changes of protein expression in Caenorhabditis elegans by mass spectrometric proteome analysis leads to the identification of stage-specific marker proteins. Electrophoresis, 24 (11): 1809-17 1-3/5 Proteom-Zentrum Rostock, Germany 4 Institut für Immunologie, Rostock, Germany
  4. Madi A1, Mikkat S2, Ringel B3, Ulbrich M4, Thiesen HJ5, Glocker MO6 (2003) IF: 5.766,Times cited: 2 Mass spectrometric proteome analysis for profiling temperature-dependent changes of protein expression in wild-type Caenorhabditis elegans. Proteomics, 3 (8): 1526-34 1-4 Proteom-Zentrum Rostock, Germany 5 Institut für Immunologie, Rostock, Germany
  5. Bantscheff M1, Ringel B2, Madi A3, Schnabel R4, Glocker MO5, Thiesen HJ6 (2004) IF: 5.7660, Times Cited: 0 Differential proteome analysis and mass spectrometric characterization of germ line development-related proteins of Caenorhabditis elegans. Proteomics, 4 (8): 2283-95 1-3/5 Proteom-Zentrum Rostock, Germany 4 TU Braunschweig, Germany 6 Institut für Immunologie, Rostock, Germany

Rheumatology

  1. Aidinis V1, Plows D2, Haralambous S3, Armaka M4, Papadopoulos P5, Kanaki MZ6, Koczan D7, Thiesen HJ8, Kollias G9 (2003) IF: 5.036, Times Cited: 4 Functional analysis of an arthritogenic synovial fibroblast. Arthritis Res Ther, 5 (3): R 140-57 1,4,5-6,9 Institute of Immunology, Biomedical Sciences Research Center "Alexander Fleming", Athens, Greece 2,3 Laboratory of Molecular Genetics, Hellenic Pasteur Institute, Athens, Greece 7,8 Institute of Immunology, University of Rostock, Germany
  2. Lorenz P1, Ruschpler P2, Koczan D3, Stiehl P4, Thiesen HJ5 (2003) IF: 5.766, Times Cited: 9 From transcriptome to proteome: differentially expressed proteins identified in synovial tissue of patients suffering from rheumatoid arthritis and osteoarthritis by an initial screen with a panel of 791 antibodies. Proteomics, 3 (6): 991-1002 1,3,5 Institut für Immunologie, Rostock, Germany 2,4 Institut für Pathologie, Leipzig, Germany
  3. Ruschpler P1, Lorenz P2, Eichler W3, Koczan D4, Hanel C5, Scholz R6, Melzer C7, Thiesen HJ8, Stiehl P9 (2003) IF: 5.036, Times Cited: 7 High CXCR3 expression in synovial mast cells associated with CXCL9 and CXCL10 expression in inflammatory synovial tissues of patients with rheumatoid arthritis. Arthritis Res Ther, 5 (5): R 241-52 1,5,9 Institute of Pathology, Leipzig, Germany 3 Eye Hospital, Leipzig,Germany 6 Department of Orthopedic Surgery, Leipzig, Germany 7 Specialty Hospital of Orthopedic and Trauma Surgery, Bad Düben, Germany 2,4,8 Institute of Immunology, Rostock, Germany
  4. Lorenz P1, Bantscheff M2, Ibrahim SM3, Thiesen HJ4, Glocker MO5 (2003) IF: 1.523, Times Cited: 1 Proteome analysis of diseased joints from mice suffering from collagen-induced arthritis. Clin Chem Lab Med, 41 (12): 1622-32 1,3,4 Institut für Immunologie, Rostock, Germany 2,5 Proteom-Zentrum Rostock, Germany
  5. Wester L1, Koczan D2, Holmberg J3, Olofsson P4, Thiesen HJ5, Holmdahl R6, Ibrahim SM7 (2003) IF: 5.036, Times Cited: 3 Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats. Arthritis Res Ther, 5 (6): R 361-72 1,2,5,7 Institut für Immunologie, Rostock, Germany 3,4,6 Medical Inflammation Research, Biomedical Center, Lund, Sweden
  6. Drynda S1, Ringel B2, Kekow M3, Kühne C4,Drynda A5, Glocker MO6, Thiesen HJ7, Kekow J8 (2004) IF:0.8210,Times cited: 1 Proteome analysis reveals disease-associated marker proteins to differentiate RA patients from other inflammatory joint diseases with the potential to monitor anti-TNFalpha therapy. Pathol Res Pract, 200 (2): 165-71 1,3-5,8 Zentrum für Innere Medizin, Klinik für Rheumatologie, Vogelsang,Germany 2,6 Proteom-Zentrum Rostock 7 Institut für Immunologie, Rostock, Germany
  7. Tu-Rapp H1, Hammermüller A2, Mix E3, Kreutzer HJ4, Goerlich R5, Köhler H6, Nizze H7, Thiesen HJ8, Ibrahim SM9 (2004) IF: 5.0360, Times Cited: 0 A proinflammatory role for Fas in joints of mice with collagen-induced arthritis. Arth Res & Ther, 6 (5): R 404-12 1,2,6,8,9 Institut für Immunologie, Rostock, Germany 3 Klinik und Poliklinik für Neurologie, Rostock,Germany 4,7 Institut für Pathologie, Rostock, Germany 5 Institut für Biologie VII, RWTH Aachen, Germany
  8. Bauer, K1, Knipper A2, Tu-Rapp H3, Koczan D4, Kreutzer HJ5, Nizze H6, Mix E7, Thiesen HJ8, Holmdahl R9, Ibrahim SM10 (2005), IF: 5.036 Perforin Deficiency attenuates Collagen-Induced Arthritis. Arthritis Research and Therapy (in press) 1-4,8,10 Institute of Immunology, Rostock, Germany 5,6 Institute of Pathology, Rostock, Germany 7 Institute of Neurology, Rostock, Germany 9 Section for Medical Inflammation Research, Lund, Sweden

Technologies

  1. Bosze Z1, Thiesen HJ2, Charnay P3 (1986) IF: 10.456, Times Cited: 50 A transcriptional enhancer with specificity for erythroid cells is located in the long terminal repeat of the Friend murine leukaemia virus. EMBO J, 5 (7): 1615-23 1-3 EMBL Heidelberg, Germany
  2. Thiesen HJ1, Bach C2 (1990) IF: 6.575, Times Cited: 160 Target Detection Assay (TDA): a versatile procedure to determine DNA binding sites as demonstrated on SP1 protein. Nucleic Acids Res, 18 (11): 3203-9 1-2 Basel Institute for Immunology, Switzerland
  3. Thiesen HJ1, Schröder B2 (1991) IF: 2.836, Times Cited: 9 Amino acid substitutions in the SP 1 zinc finger domain alter the DNA binding affinity to cognate SP 1 target site. Biochem Biophys Res Commun, 175 (1): 333-8 1-2 Basel Institute for Immunology, Switzerland
  4. Thiesen HJ1, Bach C2 (1991) IF: 3.609, Times Cited: 12 Determination of DNA binding specificities of mutated zinc finger domains. FEBS Lett, 283 (1): 23-6 1-2 Basel Institute for Immunology, Switzerland
  5. Reimer T1, Koczan D2, Briese V3, Friese K4, Richter D5, Thiesen HJ6, Jeschke U7 (2000) IF: 1.579, Timescited: 9 Absolute quantification of human chorionic gonadotropin-beta mRNA with TaqMan detection. Mol Biotechnol, 14 (1): 47-57 1,3,4,5,7 Frauenklinik und Poliklinik, Rostock, Germany 2,6 Institut für Immunologie, Rostock, Germany
  6. Kunz M1, Ibrahim SM2, Koczan D3, Scheid S4, Thiesen HJ5, Gross G6 (2004) IF: 2.040, Times Cited: 1 DNA microarray technology and its applications in dermatology. Exp Dermatol, 13 (10): 593-606 1-3,5 Institut für Immunologie, Rostock, Germany 4,6 Department of Dermatology, Rostock,Germany

Virology

  1. Thiesen HJ1, Bosze Z2, Henry L3, Charnay P4 (1988) IF: 5.225, Times Cited: 39 A DNA element responsible for the different tissue specificities of Friend and Moloney retroviral enhancers. J Virol, 62 (2): 614-8 1-4 EMBL Heidelberg, Germany
  2. Thiesen HJ1 (1996) IF:2.667,Times cited: 7 From repression domains to designer zinc finger proteins: a novel strategy of intracellular immunization against HIV. Gene Expr, 5 (4-5): 229-43 1 Institut für Immunologie, Rostock, Germany
  3. Herchenröder O1, Hahne JC2, Meyer WK3, Thiesen HJ4 Schneider J5 (1999) IF: 2.557, Times Cited: 6 Repression of the human immunodeficiency virus type 1 promoter by the human KRAB domain results in inhibition of virus production. Biochim Biophys Acta, 1445 (2): 216-23 1,5Institut für Medizinische Mikrobiologie und Hygiene, Universität Freiburg, Freiburg, Germany 2,3 Basel Institute for Immunology, Switzerland 4 Institut für Immunologie, Rostock, Germany

Reviews

  1. Thiesen HJ1, Bach C2 (1993) IF: 1.892, Times Cited: 9 DNA recognition of C2H2 zinc finger proteins. Evidence for a zinc-finger-specific DNA recognition code. Ann N Y Acad Sci, 684:246-9 1,2 Basel Institute for Immunology, Switzerland
  2. Thiesen HJ1, Koczan D2, Ibrahim SM3 (1997) IF:0, Times Cited: 3 The role of apoptosis in autoimmune disease with special reference to juveline chronic arthritis. Rev Rhum Engl Ed, 64(10 Suppl): 140S-143S 1-3 Institut für Immunologie, Rostock, Germany
  3. Kunz M1, Ibrahim SM2, Koczan D3, Scheid S4, Thiesen HJ5, Gross G6 (2004) IF: 2.0400, Times Cited: 1 DNA microarray technology and its applications in dermatology. Exp Dermatol, 13 (10): 593-606 1/4/6 Klinik und Poliklinik für Dermatologie und Venerologie, Rostock, Germany 2,3,5 Institut für Immunologie, Rostock, Germany

Monographs

  1. Annette Christoph and Hans-Jürgen Thiesen "Use of PCR to determine genomic DNA target sites for a zinc finger protein expressed in mouse cerebellum". Methods in Neurosciences 26, 414-430, 1996 (Buchbeitrag)
  2. Transcriptional gene regulation H.-J. Thiesen (Section Editor), Immunological Methods Manual, edited by Dr. Lefkovits, 309-380, 1997 (Academic Press)
  3. H.-J. Thiesen FromTransient Cotransfections to the Transcription Repressor Assay (TRA), Immunological Methods Manual, edited by Dr. Lefkovits, 315-331, 1997 (Academic Press)
  4. H.-J.Thiesen From Designer Zinc Finger Domains by Phage Display to Transcription Response Modifiers (TRM), Immunological Methods Manual, edited by Dr. Lefkovits, 365-373, 1997 (Academic Press)